CohortAutism research : official journal of the International Society for Autism Research2025

The Factor Structure and Validity of the Psychopathy Checklist-Short Version When Used With Autistic Psychiatric Inpatients.

Kate Maguire, Magali Barnoux, Josie Collins and 11 others

PMID 39963077

WHAT IT FOUND

In 282 autistic psychiatric inpatients, the PCL:SV was related to past risk and poor treatment progress, but poorly predicted aggressive or problematic behaviour over 12 months.

Key findings

01Higher PCL:SV scores were associated with longer hospital stay, more previous convictions, cautions and reprimands, and more violent offences.

02PCL:SV scores had poor ability to tell which inpatients had shown aggressive or problematic behaviour in the 12 weeks before follow-up.

03Higher PCL:SV scores were associated with lower odds of discharge and higher odds of no change or a move to higher security at 12 months.

STILL TO COME

How it was doneWhat they found

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What it does not show

Not preregistered, and data, analysis code and research materials are not available. The paper reports 282 participants, 257 PCL:SV total scores and 26 missing PCL:SV data, so the analysed count is not fully clear. Some findings changed after missing-data sensitivity analysis, including Factor 2 and Mental Health Act section. Aggressive or problematic behaviour was recorded as frequency and presence or absence, not severity, so high-frequency low-intensity autism-related behaviours may have been mixed with more serious offending behaviours. Autism symptom severity was not measured, and the authors note that autism or intellectual disability behaviours may contribute to PCL:SV scores, especially Factor 2. Forty-nine percent had an intellectual disability, and intellectual disability was associated with fewer current offences, violent offences and forensic background in several models. Clinicians knew participants' histories and records when completing the PCL:SV, and no inter-rater reliability checks were undertaken. The sample was autistic psychiatric inpatients in England and Wales, with 251 males, 30 females and one transgender person, and results do not generalise to autistic prisoners, community autistic people or other countries. The PCL:SV was poor at discriminating aggressive or problematic behaviour, so it should not be treated as a standalone behaviour prediction tool.

Declared interests

Funded by the National Institute for Health and Care Research. Authors declared no conflicts of interest.

The easy way to misread this

Do not use the PCL:SV as a standalone tool to predict aggressive or problematic behaviour in autistic inpatients. It had poor ability to discriminate these behaviours, and some behaviours may reflect autism or intellectual disability rather than psychopathy.

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The study

Participants
282 autistic inpatients; PCL:SV total score n = 257
Certainty of evidence
Low

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    Kate Maguire, Magali Barnoux, Josie Collins, et al. The Factor Structure and Validity of the Psychopathy Checklist-Short Version When Used With Autistic Psychiatric Inpatients. Autism research : official journal of the International Society for Autism Research. 2025.

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