PilotJournal of neuroengineering and rehabilitation2025

The effects of unilateral nostril breathing on brain functional network activity: a pilot study.

David E White, Usman Ghani, Mangor Pedersen and 8 others

PMID 41398294

WHAT IT FOUND

Device-controlled one-nostril breathing changed brain network activity in 30 healthy adults, but only when comparing left to right breathing against each other.

There was no significant difference between either side and their own natural breathing baseline.

Key findings

01No significant changes in functional connectivity were detected when comparing dominant or nondominant unilateral nostril breathing to the baseline natural breathing state.

02Significant frequency-specific increases and decreases in functional connectivity occurred only when comparing left-sided breathing to right-sided breathing.

03The study found that nasal morphology (left versus right side) appeared to be the controlling factor for these changes, rather than the natural nasal cycle dominance status.

STILL TO COME

How it was doneWhat they found

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What it does not show

This was a pilot study in healthy young adults, so it does not show how people with neurological conditions or injuries would respond. The study measured brain activity patterns, not clinical symptoms or functional abilities, so it does not prove that breathing changes improve or worsen any patient outcome. The significant results were only found when comparing left to right breathing, not against the person's own baseline, which makes the practical effect of the intervention unclear.

The easy way to misread this

Do not interpret these brain network changes as evidence that unilateral nostril breathing improves cognitive or physical function. The study found no significant difference between the breathing intervention and the participants' natural baseline breathing, and the results were from healthy adults without clinical symptoms.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →


The study

Participants
30
Certainty of evidence
Very low

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    Cite

    David E White, Usman Ghani, Mangor Pedersen, et al. The effects of unilateral nostril breathing on brain functional network activity: a pilot study. Journal of neuroengineering and rehabilitation. 2025.

    Read the original — we summarise, we never replace the paper.