RNMeta-AnalysisJournal of clinical nursing2026

The Effect of Theory-Guided Positive Psychological Interventions for Patients With Breast Cancer: A Systematic Review and Meta-Analysis.

Sek Ying Chair, Zehao Huang, Myrian Sze Nga Fan and 2 others

PMID 40626621

WHAT IT FOUND

Theory-guided positive psychological interventions improved quality of life in 412 breast cancer patients across five randomised trials, with moderate certainty.

Key findings

01The meta-analysis of five randomised trials found that theory-guided positive psychological interventions significantly improved quality of life, with moderate certainty.

02Interventions lasting less than 3 weeks and interventions lasting 3 weeks or longer both significantly improved quality of life, and no significant difference was found between these duration subgroups.

03One included trial reported reductions in depression and anxiety and improvement in sleep quality.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

Read the rest of this summary

You get three full summaries a month, free, and we do not ask for a card. Search, the TL;DRs and your library stay unlimited either way.

Already have one?

What it does not show

Only five randomised trials and 412 patients were included, so the evidence is limited. Only English-language studies were included, and all came from the United States, China or South Korea, so cultural and healthcare-system differences may limit generalisability. The interventions were heterogeneous, differing in content, format, duration, frequency and facilitator. Only two studies had low risk of bias across all domains, and only two were rated low risk for selective reporting. Small sample sizes and differences in breast cancer stage raise concerns about robustness. Secondary psychological and somatic outcomes were reported by too few trials to be pooled. Long-term effects were not evaluated. The review did not identify the optimal duration or frequency of intervention.

Declared interests

The authors declared no conflicts of interest. The supplied publication types note non-U.S. government research support, but the supplied text does not name the funder or describe its role.

The easy way to misread this

Do not read the pooled quality-of-life improvement as proof that one named programme works. Five different theory-guided interventions were combined, including expressive writing, mind subtraction meditation with self-management education, and family-centred online health education, and the supplied text does not report separate effects for each component.

Read it on PubMed →