The Effect of Prangos Ferulacea Vaginal Cream on Accelerating the Recovery of Bacterial Vaginosis: A Randomized Controlled Clinical Trial.
Asieh Azadpour Motlagh, Mahrokh Dolatian, Faraze Mojab and 6 others
PMID 29607339WHAT IT FOUND
Adding Prangos ferulacea vaginal cream to oral metronidazole cleared bacterial vaginosis symptoms faster than metronidazole alone.
Symptoms subsided in 78% of the combination group by day three, compared to 38% in the control group. Full recovery by day four occurred in 78% versus 30%.
Key findings
01Symptoms subsided significantly faster in the group receiving oral metronidazole plus Prangos ferulacea vaginal cream (78% by day 3) compared to oral metronidazole alone (38% by day 3).
02Full recovery by the end of the fourth day was achieved in 78% of the combination group versus 30% of the metronidazole-only group.
03There were no significant differences in medication side effects between the two groups, with no patients in the Prangos ferulacea group experiencing stomach ache.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study did not follow up patients who experienced recurrence of the disease. Both groups received oral metronidazole, so the study tests the addition of the cream to standard care, not the cream as a standalone treatment. The sample size was relatively small (100 participants).
Declared interests
No specific funding source or conflict of interest declaration was provided in the text.
The easy way to misread this
Do not interpret this as evidence that Prangos ferulacea cream works without antibiotics. Both groups received oral metronidazole, so the benefit observed was in speed of recovery when adding the cream to standard treatment, not as a monotherapy.