RNProtocolResearch in nursing & health2022

Sleep disruption and delirium in critically ill children: Study protocol feasibility.

Laura Beth Kalvas, Tondi M Harrison, Sandra Solove and 1 others

PMID 35986659

WHAT IT FOUND

Feasibility of monitoring sleep, light, sound, caregiving and delirium in 10 PICU children was mixed.

Recruitment was 48%, retention was 100%, and short stays shortened the planned endpoint to 10 hours. This tested measurement methods, not whether sleep or delirium were caused.

Key findings

01Of 25 families approached, 12 were recruited (48%), and retention was 100%.

02PICU length of stay was short: 70% stayed less than 48 hours, and the monitoring endpoint was shortened to 10 hours.

03Six children (60%) screened positive for delirium at least once during participation.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

Only 10 children were analysed, and they were a convenience sample, so these feasibility numbers are small and may not apply to other PICUs. The study changed its endpoint from 48 hours to 10 hours because many children left the PICU early, so it did not capture the planned amount of sleep and environment data. Most children were young and not very ill: 90% were 2 years or less, median PRISM III score was 2.50, and none needed mechanical ventilation, so it says little about sicker or older children. Children with expected stays under 48 hours, deep sedation, restraints, sensory impairment, chronic critical illness, or anesthesia exposure were excluded, limiting generalisability. Video-based delirium screening had lower agreement than expected, and some screens were missed when children were asleep or video quality was poor. The pilot did not analyse whether sleep, light, sound or caregiving were associated with delirium; those data were not reported here. Family and staff feedback was not formally collected, and all four English-as-a-second-language families approached refused, partly because of video recording. The protocol was costly and time-intensive, which limits its use as routine clinical care.

Declared interests

One author, Tondi M. Harrison, is an Executive Editor at Research in nursing & health. The authors declared no other conflicts of interest.

The easy way to misread this

Do not read the 60% delirium rate as proof that sleep disruption caused delirium. This was a 10-child feasibility pilot, not a test of cause or treatment, and the sleep and delirium data analysis was not reported here.

Read it on PubMed →

Sleep disruption and delirium in critically ill children: Study protocol feasibility. — Applied Evidence