PTOTCohortJournal of physical therapy science2026

Short-term changes in frailty status and associated factors over 3 months of multidisciplinary outpatient care in older adults.

Keisuke Nakamura, Yuya Nagasawa, Masayuki Shimizu

PMID 42703461

WHAT IT FOUND

Half of 100 older adults improved frailty over 3 months.

Daily home exercise was associated with improvement, but medical, nutrition, exercise, supervised rehab, nursing and social support were given together, so no single component can be credited.

Key findings

0151 of the 100 participants improved frailty status.

02The proportion classified as frail fell from 31% to 11%, and the proportion classified as robust rose to 35%.

03Participants who did home exercise daily were more likely to improve than those who exercised several days per week or not at all.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

There was no control group, so the study cannot show that the clinic caused the changes. The 3-month follow-up was short, so it does not show whether changes lasted. Participants were outpatients from one hospital clinic, so results may not apply elsewhere. Only people who completed both baseline and 3-month assessments were analysed. Home exercise frequency was self-recorded on weekly logs and was not objectively verified. People who could exercise daily may have been healthier to begin with, so reverse causality is possible. Missing data were imputed, and some variables had missing values, so residual bias or confounding could remain. Medical review, nutrition counselling, exercise instruction, supervised rehabilitation, nursing guidance and social support were delivered together, so no single component can be credited.

Declared interests

This work was supported by Japan Society for the Promotion of Science KAKENHI grant 24K20496. The authors declare no potential conflicts of interest concerning authorship and publication.

The easy way to misread this

Do not conclude that the frailty clinic or home exercise caused frailty improvement. Medical review, nutrition counselling, exercise instruction, supervised rehabilitation, nursing guidance and social support were delivered together, the study had no control group, and home exercise frequency was self-reported.

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