RNCohortThe journal of nursing research : JNR2026

Role of Sense of Coherence in Mediating the Relationship Between End-of-Life Caregiving Burden and Bereavement Depressive-Symptom Trajectory.

Fur-Hsing Wen, Wen-Chi Chou, Ming-Mo Hou and 5 others

PMID 41805659

WHAT IT FOUND

Family caregivers who felt end-of-life demands were understandable, manageable, and meaningful were more likely to show low or resolving depression after bereavement in this observational study.

Key findings

01Caregivers with lower perceived end-of-life caregiving burden reported higher sense-of-coherence scores than those with severe burden.

02Stronger sense of coherence was associated with less distressing depression trajectories in 15 of 21 comparisons.

03Adding sense of coherence to the models reduced significant associations between caregiving burden and depression trajectories from 31 to 19.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The sample was a convenience sample from one hospital in Taiwan, mostly spouses or adult children of patients with advanced cancer, so findings may not apply to other cultures, diseases, sudden deaths, or caregiver roles. Depression was measured with a symptom questionnaire rather than a formal psychiatric diagnosis, which may overestimate severity. Follow-up covered only the first 2 years after death. Sense of coherence was measured once and treated as stable, though it may change over time. Some combined burden and depression trajectory groups were small. Estimates may be imprecise. Other factors such as social support, coping strategies, and stressors beyond gender and age were not measured. They may explain part of the association.

Declared interests

No funding source or conflicts of interest are reported in the supplied text.

The easy way to misread this

Do not conclude that strengthening sense of coherence will prevent caregiver depression. This was an observational study of associations, and it did not test an intervention or show that changing sense of coherence changes depression trajectories.

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