Risk prediction and impaired tactile sensory perception among cancer patients during chemotherapy.
Ana Carolina Lima Ramos Cardoso, Diego Dias de Araújo, Tânia Couto Machado Chianca
PMID 29319742WHAT IT FOUND
Fifty-seven percent of adult cancer patients receiving chemotherapy developed impaired tactile sensory perception during treatment.
Lower-limb discomfort, hepatic metastases, and alcoholism predicted faster onset of this sensory loss.
Key findings
01Impaired tactile sensory perception occurred in 57% of adult cancer patients receiving antineoplastic chemotherapy.
02Hepatic metastases, alcoholism, and lower-limb discomfort were associated with a significantly faster onset of impaired tactile sensory perception.
03Peripheral venous access and palliative chemotherapy were associated with a slower onset of impaired tactile sensory perception.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study relied entirely on data recorded in medical files, which may be incomplete or inconsistent. It was conducted at a single medium-sized private hospital, limiting generalisability to other settings. The sample size was small (127 patients), and the finding that palliative chemotherapy and peripheral venous access were protective contradicts existing literature, suggesting these results may be unstable.
The easy way to misread this
Do not assume that palliative chemotherapy or peripheral venous access protects against sensory neuropathy. These associations were unexpected and diverge from established literature, likely reflecting confounding factors in this specific retrospective sample rather than a true protective effect.