Relationship of locomotive syndrome with health-related quality of life among patients with obstructive sleep apnea syndrome.
Hiroaki Kataoka, Nobuyuki Miyatake, Hirohisa Ichikawa and 2 others
PMID 28744031WHAT IT FOUND
Of 1,195 Japanese patients with sleep apnea treated with CPAP, 578 screened positive for locomotive syndrome (mobility and balance problems).
Those with it reported lower quality of life after accounting for age, body mass, apnea severity, and sleepiness.
Key findings
01In 1,195 Japanese outpatients with obstructive sleep apnea syndrome treated with CPAP, 578 (48.4%) screened positive for locomotive syndrome.
02Patients with locomotive syndrome had lower quality-of-life scores, and this remained after accounting for age, gender, BMI, OSAS duration, AHI, and JESS score.
03Locomotive syndrome had the strongest association with lower quality-of-life scores among the factors examined.
STILL TO COME
How it was doneWhat they foundWhat it means for PTs
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What it does not show
The study was cross-sectional, so it can show association but cannot show that locomotive syndrome caused lower quality of life or that locomotive syndrome developed because of sleep apnea. All participants were already treated with CPAP and were described as relatively well controlled, so the results may not apply to people with sleep apnea who are untreated or less controlled. The loco-check counted a possible case if the person agreed with at least one of seven statements, so a positive screen may be common and may not mean confirmed locomotive syndrome. Patients with musculoskeletal, neurological, endocrine, or stroke history were excluded, so the findings do not cover patients whose mobility problems may have other clear causes. The study was done at a hospital in Japan, so the prevalence and associations may not match other settings.
Declared interests
The authors declared no financial or personal relationships that could pose a conflict of interest.
The easy way to misread this
Do not conclude that locomotive syndrome causes lower quality of life or that exercise therapy will improve sleep apnea. The study was cross-sectional and only measured possible locomotive syndrome with a questionnaire; no exercise intervention was tested.