Relationship between maternal egg consumption during lactation and the risk of developing egg allergies in 12-month-old infants: A multicenter cohort study.
Sakurako Kishino, Kaori Yonezawa, Megumi Haruna and 9 others
PMID 39581860WHAT IT FOUND
Maternal egg consumption at 1 month after birth was not associated with egg allergy in 12-month-old infants.
Infants with eczema at 6 months were more likely to have egg allergy at 12 months.
Key findings
01Maternal egg consumption at 1 month, breastfeeding rate at 1 month, and breastfeeding-dependent egg consumption at 1 month were not significantly associated with egg allergy in 12-month-old infants.
02Infants with eczema at 6 months had higher odds of egg allergy at 12 months (adjusted odds ratio 3.59; 95% CI 1.59 to 8.13).
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
Only 420 of 1374 live infants were analysed, because many did not complete all questionnaires or were excluded, so the sample may not represent all infants. The mothers were highly educated (70.3% had university or graduate education), and all were recruited during the early COVID-19 period, which may limit generalizability. Egg intake, breastfeeding, eczema, and egg allergy were self-reported, and egg protein in breast milk and environmental egg protein were not measured. The analysis had few egg allergy cases (27), so it may have missed smaller effects. This is a cohort study, so it shows association, not cause.
Declared interests
The authors declared no conflict of interest. The study was funded by the Japan Society for the Promotion of Science.
The easy way to misread this
Do not conclude that eating more eggs during breastfeeding prevents infant egg allergy. Maternal egg consumption at 1 month and breastfeeding-dependent egg consumption at 1 month were not significantly associated with egg allergy at 12 months, and this was an observational cohort, not a trial.