Relationship between diagnostic characteristics, lifestyle habits and breast cancer subtypes in women.
Fernanda Cristina Marin, Clóvis Arlindo de Sousa, Erika de Sá Vieira Abuchaim and 1 others
PMID 40667946WHAT IT FOUND
Among women with breast cancer, younger age at diagnosis was linked to triple-negative disease.
Daily processed foods and soft drink or artificial juice use were linked to ductal carcinoma type. The study cannot show these habits caused the cancer type.
Key findings
01Age at diagnosis was significantly associated with molecular subtype; women under 40 predominantly presented luminal B and triple-negative subtypes.
02Daily processed-food intake was significantly associated with histological subtype; among 271 women reporting daily intake, 243 had ductal carcinoma.
03No significant associations were found between lifestyle habits and molecular subtypes.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
Lifestyle information was self-reported, so it may contain memory errors or inaccurate measurement. The study included only women diagnosed with breast cancer who were in treatment or follow-up at one centre, so results may not represent all women with breast cancer. Because only diagnosed and treated women were included, associations may be distorted by survival bias. The pandemic forced telephone interviews and caused delays, which may have affected the depth and quality of information. The cross-sectional design cannot show cause and effect. Six women lacked immunohistochemistry data, so molecular subtype analyses included 317 women.
Declared interests
The supplied text does not report conflicts of interest or funding.
The easy way to misread this
Do not conclude that avoiding processed foods or soft drinks prevents ductal carcinoma. The study observed women after diagnosis and found associations only; it did not test whether changing these habits changes cancer subtype.