Predictors of Participation in Clinical Research.

People who disliked research may have been less likely to complete the survey, so negative attitudes could be undercounted. Data were collected from 2014 to 2016, so views may have changed. A precise response rate could not be calculated because existing survey data were used. Many correlations were run across attitudes, trust, education, and race, increasing the chance of false positive findings. The design was cross-sectional, so trust or education cannot be shown to cause participation barriers. Several racial groups were very small, including Middle Eastern (9) and Native Hawaiian (4), so subgroup conclusions are unstable. The sample was mostly White (77.4%) and had at least 2 years of college education (85.8%), so it may not represent groups with less education or different racial backgrounds.

The supplied text does not include a conflicts-of-interest statement. The publication types list NIH and non-U.S. government research support.

Do not conclude that higher trust causes research participation or that education is irrelevant. The study measured attitudes in a cross-sectional survey, not actual enrollment, and some racial groups were very small.