Predictors of death within 6 months of stroke onset: A model with Barthel index, platelet/lymphocyte ratio and serum albumin.
Ling Sha, Tiantian Xu, Xijuan Ge and 3 others
PMID 33378600WHAT IT FOUND
Barthel Index, platelet/lymphocyte ratio and albumin were linked with death within 6 months in 210 Chinese stroke patients.
More dependence, higher ratio and lower albumin marked higher risk.
Key findings
01Barthel Index, platelet/lymphocyte ratio and serum albumin were independent predictors of death within 6 months, with odds ratios 0.980, 1.005 and 0.854.
02The model's discrimination was 0.879 in the training set and 0.891 in bootstrap validation.
03In time-dependent Cox analysis, Barthel Index, platelet/lymphocyte ratio and serum albumin remained independent prognostic factors, while age alone was not independent.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study was retrospective and included 210 patients from a tertiary hospital in Jiangsu, China, so it may not apply to other settings. Most patients lived near the hospital, so the sample may not represent other regions. The model had internal validation only, with no external validation. Missing values were filled before analysis, so some information may be incomplete. The study was observational, so it cannot show that changing Barthel Index, platelet/lymphocyte ratio or albumin reduces death.
Declared interests
The authors declared no conflicts of interest.
The easy way to misread this
Do not conclude that more nursing care, better nutrition or lowering platelet/lymphocyte ratio will reduce death. This was an observational model in 210 patients with internal validation only, so it shows prediction, not treatment effect.