Physical activity levels are low in the days, weeks, and months following dysvascular major lower limb amputation.
Aniek M Kolen, Leonie A Krops, Harriët Jager-Wittenaar and 11 others
PMID 42084203WHAT IT FOUND
Physical activity increases over the first nine months after dysvascular major lower limb amputation, but remains low.
Older age and undernutrition were associated with less activity, while higher grip strength was linked to more. Most activity occurred during leisure time via walking or wheeling.
Key findings
01Median questionnaire-assessed physical activity rose from 240 minutes per week at 2-12 days post-amputation to 885 minutes per week at 9 months, though this remained a low level overall.
02Accelerometer data showed daily physical activity increased from 5 minutes at the earliest time point to 54 minutes per day at 9 months, with sedentary time remaining high at approximately 1354 to 1400 minutes per day throughout.
03In univariate analysis, older age and undernutrition were associated with lower physical activity, while greater grip strength was associated with higher physical activity.
STILL TO COME
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What it does not show
A significant number of participants declined to wear the accelerometer, and those who did wear it for fewer than 4 days were still included, which may affect data reliability. The study did not perform statistical analysis on the accelerometer data due to the limited sample size at each time point. Self-reported physical activity may be subject to recall bias or inaccuracies in intensity perception, particularly given the altered biomechanics post-amputation. The accelerometer placement on the intact leg may have missed upper body activity or specific wheelchair propulsion nuances not captured by leg counts. The study population was restricted to dysvascular amputations, so findings may not apply to traumatic or cancer-related amputations.
Declared interests
The authors declared no conflicts of interest. The study was financially supported by Stichting Beatrixoord Noord-Nederland, which provided the Activ8 devices and scales. The funders had no role in study design, data collection, analysis, or manuscript preparation.
The easy way to misread this
Do not interpret the increase in physical activity over time as evidence that standard care is sufficient to achieve healthy activity levels. Activity remained low throughout the nine months, and the study was observational, so it cannot determine if specific interventions would have improved these outcomes.
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