RNCohortProgress in transplantation (Aliso Viejo, Calif.)2026

Pharmacy Resident Performed Longitudinal Medication Adherence Assessments in Candidates for Deceased Donor Kidney Transplant.

Ruchi Sane, Linh Nguyen, Srijan Tandukar and 7 others

PMID 42549785

WHAT IT FOUND

Among kidney transplant candidates followed by pharmacy residents, 95 of 193 reported improvement in at least one medication adherence tool category between first and last calls.

Dose reminder use was 21.2% then 44.0%. Listing status was unclear.

Key findings

01Between the first and last KACE encounters, 95 of 193 candidates had at least 1 category of medication adherence tool usage improvement.

02The largest reported increase was dose reminder use, 21.2% at the initial encounter and 44.0% at the last encounter.

03Six months after the last encounter, 98 of 193 candidates were never listed for transplant.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

Single-center retrospective chart review with no control group, so the study cannot show that the medication adherence program caused the reported changes. Candidates were referred by transplant team members, so selection bias is possible. Actual resident time was not documented; estimated hours came from transplant pharmacists' experience and may underestimate resident workload. Documentation templates could be edited, and free-text entries required interpretation by investigators. Listing status 6 months after the last encounter could not separate candidates who were not transplant candidates from those still undergoing evaluation. Medical, surgical, and psychosocial factors affecting listing decisions were not captured. Assignment of candidates to pharmacists versus residents could introduce bias, because one-time assessments and new candidates in 2023-2024 were often handled by pharmacists. KACE often began 89 days after initial transplant evaluation, which may be later than intended. Post-transplant medication adherence and transplant outcomes were not assessed.

Declared interests

No funding or conflict-of-interest declaration is included in the supplied text.

The easy way to misread this

Do not read the increase in medication adherence tool use as proof that KACE improves adherence or transplant listing. The study had no control group, actual resident time was estimated, and listing status could not separate candidates still being evaluated from those not listed.

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