Penicillin G Benzathine management in Primary Health Care: nursing's perspective.
Giovanna Martins Biondi, Daniela Sanches Couto, Lívia Cristina Scalon da Costa Perinoti and 3 others
PMID 42138843WHAT IT FOUND
Nurses in Brazilian primary care often skip standardized allergy history checks before giving penicillin, despite high confidence in the drug's safety.
Most reported needle blockages and incomplete dilution, and over half felt unsafe managing potential adverse reactions.
Key findings
01Over half of participants did not feel safe dealing with possible adverse reactions from penicillin administration.
02Needle obstruction was the most frequent complication during administration, reported by 84% of participants.
03While 82% considered asking about previous allergic reactions relevant, there was no standardization in how allergy history was collected.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study used a convenience sample without a sample size calculation, which limits the generalizability of the findings. Data relied on self-reporting, which introduces the possibility of recall bias. The questionnaire instrument had not undergone formal validity testing.
Declared interests
The text does not explicitly state funding sources or conflicts of interest, but notes the study was approved by a university ethics committee and followed data protection laws.
The easy way to misread this
Do not interpret the high rate of reported technical complications like needle obstruction as evidence of drug instability or poor quality control. These are procedural issues related to preparation and administration technique, not inherent flaws in the medication itself.