Patient Satisfaction Using Hybrid Cooperative Complexes of Hyaluronic Acid for Neck Laxity: A Survey of Asian Populations.
Lam Bee Lan, Leo Kah Woon, Siew Tuck Wah and 7 others
PMID 40627798WHAT IT FOUND
Patients receiving Profhilo neck injections reported low pain (all scores ≤5 on a 10-point scale) and Day 90 improvement ratings of improved, much improved or very much improved; physician neck laxity grades decreased.
This small uncontrolled survey cannot show the injection caused the change.
Key findings
01Physician-rated neck skin laxity grades decreased from baseline to Day 90, and the mean baseline-to-Day 90 change was significant in all participants (p < .0001).
02Injection pain was low: all patient-reported VAS pain scores were ≤5 on the 10-point scale.
03By Day 90, all participants reported levels of improvement as improved, much improved, or very much improved.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
Only 26 participants were studied, and the paper states the sample size is small. This was a real-world satisfaction survey, not a randomised trial with a control group, so it cannot show that the injection caused the reported changes. Participants were enrolled from routine practice and only if willing to answer surveys, so they may not represent all patients. Some authors are employees of IBSA Farmaceutici Italia, the company identified as making Profhilo. The satisfaction questions were not a standardized questionnaire; the authors recommend developing one for future studies. Follow-up was only to Day 90.
Declared interests
The paper states that some authors are employees of IBSA Farmaceutici Italia, the company identified as making Profhilo, and other authors declared no financial conflicts of interest.
The easy way to misread this
Do not conclude that Profhilo injections improve neck laxity. This was a small, uncontrolled satisfaction survey with no comparison group, so it cannot show that the injection caused the reported changes.