PTOTSLPCohortJMIR rehabilitation and assistive technologies2022

Patient Outcomes and Lessons Learned From Treating Patients With Severe COVID-19 at a Long-term Acute Care Hospital: Single-Center Retrospective Study.

Pete Grevelding, Henry Charles Hrdlicka, Steve Holland and 5 others

PMID 35023835

WHAT IT FOUND

Patients with severe COVID-19 admitted to a long-term acute care hospital improved in walking distance, independence, swallowing, voicing, and cognition during stay.

They showed larger gains in walking and independence than a historical group. This was observational, not a tested intervention.

Key findings

01Gait distance rose from a mean of 27.5 feet at admission to 248.7 feet at discharge in the COVID-19 cohort, and the increase from admission to discharge was greater than in the reference cohort (221.2 vs 142.5 feet).

02Ambulation FIM scores rose from 2.4 to 4.9 in the COVID-19 cohort and from 2.73 to 4.1 in the reference cohort, and the gain was larger in the COVID-19 cohort (2.5 vs 1.3 points).

03Among 75 patients evaluated for cognitive-communication, 72% were at baseline or within functional limits at discharge, and the mean score at discharge was 7.8, a significant improvement from admission.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

This was a retrospective single-center record review, so it describes outcomes and usual care rather than proving that any specific treatment caused improvement. The comparison group was historical, not concurrent, and the authors used a shorter time frame, which can introduce differences in patient mix, staffing, and treatment practices. Sample size was not planned before the study, and some comparisons were underpowered, especially ventilator weaning, where the reference cohort had only 7 mechanically ventilated patients. Functional outcome comparisons were incomplete: complete admission and discharge gait and FIM data were available for 99 of 127 COVID-19 admissions and 90 of 170 reference admissions. Cognitive-communication outcomes could not be compared with the reference cohort because the needed values were not readily available. Treatment practices changed during the pandemic, and some patients may have received less therapy intensity because of isolation and droplet precautions. The cohort included patients selected or prioritized for LTACH care, including health care workers and first responders when beds were scarce, so it may not represent all severe COVID-19 patients.

The easy way to misread this

Do not conclude that this LTACH rehabilitation program caused the improvements. The study was retrospective, used a historical comparison group, did not randomize patients, and did not test a specific intervention, so it cannot separate the effect of any single component of care.

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The study

Participants
117 individuals in the COVID-19 cohort (127 admissions, 118 discharges) and 157 individuals in the reference cohort (170 admissions and discharges)
Certainty of evidence
Low

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Cite

Pete Grevelding, Henry Charles Hrdlicka, Steve Holland, et al. Patient Outcomes and Lessons Learned From Treating Patients With Severe COVID-19 at a Long-term Acute Care Hospital: Single-Center Retrospective Study. JMIR rehabilitation and assistive technologies. 2022.

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