RNCohortThe Journal of the Association of Nurses in AIDS Care : JANAC2022

Pathways From Recent Incarceration to Antiretroviral Therapy Adherence: Opportunities for Interventions to Support Women Living With HIV Post Release From Correctional Facilities.

Margaret Erickson, Andrea Krüsi, Kate Shannon and 5 others

PMID 36656092

WHAT IT FOUND

Recent incarceration was not directly associated with optimal ART adherence (≥95%) among women living with HIV.

Homelessness, criminalized substance use and gender-based violence in the last 6 months were linked to lower adherence.

Key findings

01Recent incarceration was not directly associated with optimal ART adherence; indirect paths suggested mediation by recent homelessness, criminalized substance use and gender-based violence.

02Recent homelessness, criminalized substance use and gender-based violence each had significant negative direct effects on optimal ART adherence.

03Recent incarceration was significantly associated with recent homelessness, criminalized substance use and gender-based violence.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The study is observational, so the pathways cannot be interpreted as causal, and reverse directionality between incarceration and the mediators is possible. ART adherence was self-reported rather than measured by viral load, and self-report can be affected by social desirability. Only 8.9% of participants had recent incarceration at baseline, and the authors could not stratify the path analysis by race or gender identity because of small numbers. The sample was drawn from one Metro Vancouver cohort of marginalized women living with HIV, with high rates of Indigenous identity, mental health diagnosis and substance use, so it may not represent other settings. The study identified associations with housing, substance use and violence, but it did not test whether housing, harm-reduction or violence services improve ART adherence.

Declared interests

The supplied article metadata lists NIH extramural and non-U.S. government research support. No author conflict-of-interest declaration is included in the supplied text.

The easy way to misread this

Do not conclude that incarceration itself directly caused poor ART adherence or that housing, substance-use or violence services will improve adherence. The direct path from recent incarceration to adherence was not significant, and this observational study used self-reported adherence and cannot prove causation.

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