RNCohortHeart & lung : the journal of critical care2021

Outcomes of patients with COVID-19 in the intensive care unit in Mexico: A multicenter observational study.

Silvio A Ñamendys-Silva, Pedro E Alvarado-Ávila, Guillermo Domínguez-Cherit and 15 others

PMID 33138974

WHAT IT FOUND

In critically ill COVID-19 patients, older age and higher C-reactive protein on ICU admission were linked to higher death risk.

Longer ICU stay was linked to lower risk. 51.8% of patients died within 30 days.

Key findings

0151.8% of the 164 critically ill patients died at or before 30 days.

02Older age and higher C-reactive protein levels upon ICU admission were independently associated with increased in-hospital mortality risk.

03Longer ICU length of stay was associated with reduced in-hospital mortality risk.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The study had a small sample size, which may limit the generalizability of the findings. The observational nature of the study means that causality cannot be established. There was no information on long-term outcomes or quality of life for survivors. No on-site monitoring was performed, relying on data reported by each center.

Declared interests

The authors state that there are no conflicts of interest related to this study, and there was no funding to report.

The easy way to misread this

Do not interpret the association between longer ICU stay and lower mortality as evidence that keeping patients in the ICU longer improves survival. This is likely an artifact of survivorship bias, where patients who died early had shorter stays, while those who survived longer required more time in the ICU.

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