PTOTSystematic ReviewClinical rehabilitation2026

Outcome measures in prehabilitation interventions for total hip and knee arthroplasty: A scoping review.

Nicola Burgess, Stefanie N Voelker, Belinda Phillips and 4 others

PMID 40971560

WHAT IT FOUND

Trials testing pre-surgery exercises for hip and knee replacements use vastly different outcome measures, making it hard to compare results.

Patient-reported scores and length of stay are most common, but few trials align with recommended core domains or define prehabilitation clearly.

Key findings

01The review included 92 unique trials with a total of 6684 participants, averaging 72.7 participants per trial.

02Patient-reported outcomes were the most frequently collected domain, reported in 85 trials, followed by performance-based outcomes in 61 trials.

03Alignment with the 2017 core domain set was poor and did not improve after the guidelines were published, with satisfaction and cost rarely reported.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

The review only included English-language randomised controlled trials, which may miss relevant studies from non-English speaking countries or other designs. Methodological quality of the included trials was not assessed, as is standard for scoping reviews, so the reliability of the reported outcomes is unknown. The alignment analysis assumed full instrument use unless stated otherwise, which may overestimate domain coverage. The search was updated in May 2025, but rapid changes in prehabilitation research mean some very recent trials may not be included.

Declared interests

The authors received no financial support for the research. Professor Denehy has received support for educational presentations on prehabilitation from Roche and Bristol Myers Squibb. All other authors declared no conflicts of interest.

The easy way to misread this

Do not interpret the high frequency of patient-reported outcomes and length of stay as evidence that these are the most valid or clinically meaningful measures. They are simply the most commonly collected, and the review explicitly states that alignment with recommended core domains is poor, meaning important outcomes like satisfaction and cost are largely missing from the evidence base.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →