Outcome measures for economic evaluations and cost-effectiveness analyses of interventions for people with intellectual disabilities: A methodological systematic review.
Valerio Benedetto, Luís Filipe, Catherine Harris and 3 others
PMID 36448370WHAT IT FOUND
Usual quality-of-life questionnaires like the EQ-5D can be hard for people with intellectual disabilities to answer and may miss caregiver effects.
Only three studies were found. Alternatives still need testing in this population.
Key findings
01Only three studies met the review's inclusion criteria, and all three discussed instruments used to collect health-state data.
02The included qualitative evaluation recommended that the EQ-5D should not be used as the sole measure of health-related quality of life for people with intellectual disabilities.
03The included methodological study identified caregiver health and economic effects, and family effects, as spillover effects relevant to interventions for children with intellectual disabilities.
STILL TO COME
How it was doneWhat they found
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What it does not show
Only three studies met the review's inclusion criteria, so the arguments rest on a very small evidence base. The review did not formally assess the quality of the included studies, so the strength of the extracted arguments was judged during synthesis. Some included studies covered intellectual disabilities as part of broader neurodevelopmental disorders, not only intellectual disabilities. The searches were limited to English-language records. The review focused on outcome measurement, not on costs, time horizons, or modelling choices.
Declared interests
The authors declared no conflict of interest.
The easy way to misread this
Do not read this as proof that standard quality-of-life measures are unusable for people with intellectual disabilities. The review found only three methodological studies, and it did not test patient outcomes from an intervention.