Onset factors of infective and non-infective complications in perioperative gastrointestinal cancer patients.
Tsuyoshi Hara, Eisuke Kogure, Akira Kubo
PMID 31417213WHAT IT FOUND
After gastrointestinal cancer surgery, more blood loss and higher CRP level on day 3 were linked to infective complications.
Lower preoperative respiratory function was also linked. Longer operation time was linked to non-infective complications. This study cannot prove cause.
Key findings
01Blood loss, CRP level on POD3, and FEV1.0% were linked to infective complications in the model.
02Surgical time was linked to non-infective complications in the model.
03The infective complication group differed from the non-complication group on operation time, blood loss, CRP-POD3, FEV1.0%, six-minute walking distance, body mass index, and visceral fat area.
STILL TO COME
How it was doneWhat they foundWhat it means for PTs
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What it does not show
The study did not assign treatment, so it cannot show that these factors caused complications. Only 23 patients had infective complications and 17 had non-infective complications, so the groups were small. Patients had to score perfectly on the Functional Independence Measure before surgery and at home, so people with lower independence were excluded. Data came from records and only one month of follow-up, which may miss later complications. Seventy of 189 patients were excluded, including those with missing data, so the analysed sample may not represent all surgical patients.
Declared interests
The authors declared no funding or conflicts of interest.
The easy way to misread this
Do not conclude that preoperative physical therapy prevents complications. This study only linked preoperative measures to complications; it did not test a therapy programme.