CohortJournal of autism and developmental disorders2026

Oculomotor Function in Children and Adolescents with Autism, ADHD or Co-occurring Autism and ADHD.

Elana J Forbes, Jeggan Tiego, Joshua Langmead and 15 others

PMID 39856431

WHAT IT FOUND

Children and adolescents with autism plus ADHD ended rapid eye movements in less consistent positions than neurotypical peers.

Autistic children and adolescents made more corrective eye movements while tracking a moving target.

Key findings

01Children and adolescents with autism plus ADHD had greater variability in final eye position than neurotypical peers.

02Autistic children and adolescents made more catch-up saccades than neurotypical peers during step-ramp tracking.

03The main cohort showed no significant anti-saccade group differences, and the Nottingham confirmatory cohort showed no significant oculomotor group differences.

STILL TO COME

How it was doneWhat they found

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What it does not show

The study measured eye movements at one time point and did not test treatment, so it cannot show that eye movement differences cause autism or ADHD or that therapy can change them. The anti-saccade task had limited usable data: only 116 participants had valid data, and 121 participants were excluded because they could not complete at least 6 viable trials. The main findings were not replicated in the Nottingham confirmatory cohort, which included 101 children and adolescents. The sample was broad, from 4 to 18 years, and age was adjusted for rather than compared in narrow age groups. Some participants had additional conditions such as anxiety, which may affect eye movements. Group sizes were unequal, which the authors note may reduce power.

Declared interests

The supplied text lists funding from the Medical Research Future Fund (EPCD000002), an Australian Government Research Training Program Scholarship, a National Health and Medical Research Council Senior Research Fellowship (1154378), an NHMRC Investigator Grant L2, and Monash University. It does not report author competing interests.

The easy way to misread this

Do not read these eye movement differences as a diagnostic test or as evidence that a treatment will help autism or ADHD. The paper reports group comparisons, not diagnostic accuracy or treatment outcomes.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →


The study

Participants
405 children and adolescents in the main MAGNET cohort; 101 in the Nottingham confirmatory cohort; 29 autistic and 41 neurotypical in the Kansas confirmatory cohort
Certainty of evidence
Low

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    Cite

    Elana J Forbes, Jeggan Tiego, Joshua Langmead, et al. Oculomotor Function in Children and Adolescents with Autism, ADHD or Co-occurring Autism and ADHD. Journal of autism and developmental disorders. 2026.

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