RNOtherJournal of the American Medical Directors Association2022

Nursing Home Characteristics Associated with High and Low Levels of Antipsychotic, Benzodiazepine, and Opioid Prescribing to Residents with Alzheimer's Disease and Related Dementias: A Cross-Sectional Analysis.

Molly Candon, Julie Strominger, Evelyn Gotlieb and 1 others

PMID 35772472

WHAT IT FOUND

Nursing homes with higher antipsychotic prescribing for residents with dementia also had higher benzodiazepine prescribing.

Opioid prescribing did not track the same way. These are facility associations, not tested causes.

Key findings

01The average nursing-home share of residents with Alzheimer's disease or related dementias who received at least one antipsychotic, benzodiazepine, or opioid prescription during 2017 was 29.1%, 30.2%, and 40.9%, respectively.

02Nursing homes in the top quartile of antipsychotic prescribing were significantly more likely to be in the top quartile of benzodiazepine prescribing by 11.1 percentage points, and nursing homes in the bottom quartile of antipsychotic prescribing were significantly more likely to be in the bottom quartile of benzodiazepine prescribing by 8.6 percentage points.

03Opioid prescribing did not track antipsychotic prescribing as consistently: nursing homes in the top antipsychotic quartile were less likely to be in the top opioid quartile by 4.4 percentage points, and nursing homes in the bottom antipsychotic quartile were slightly less likely to be in the bottom opioid quartile by 2.3 percentage points.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The analysis is cross-sectional, so it can estimate associations but cannot show that nursing-home characteristics caused prescribing differences. Prescription fills were used as a proxy for medication use, so the study could not determine why medications were prescribed or whether they were appropriate. The sample included only older adults with Alzheimer's disease or related dementias in fee-for-service Medicare with Part D coverage and in nursing homes with at least 10 residents with Alzheimer's disease or related dementias, so it may not apply to Medicare Advantage residents or smaller nursing homes. Models were estimated at the nursing-home level, which may create aggregation bias; resident-level studies are needed to understand individual prescribing. The study did not test whether the associations are dynamic over time or whether the effect sizes are clinically meaningful. Interaction effects between nursing-home characteristics, such as nursing care and Medicaid payer mix, were not explored.

Declared interests

The supplied text does not report author financial conflicts. LTCFocus data are sponsored by the National Institute on Aging through a cooperative agreement with Brown University School of Public Health.

The easy way to misread this

Do not conclude that facility characteristics such as registered nurse staffing cause lower prescribing. The study is cross-sectional, uses prescription fills as proxies for medication use, and cannot show whether medications were appropriate.

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The study

Participants
448,128 Medicare beneficiaries with Alzheimer's disease or related dementias in 13,151 nursing homes
Certainty of evidence
Low

More in older adults

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Cite

Molly Candon, Julie Strominger, Evelyn Gotlieb, et al. Nursing Home Characteristics Associated with High and Low Levels of Antipsychotic, Benzodiazepine, and Opioid Prescribing to Residents with Alzheimer's Disease and Related Dementias: A Cross-Sectional Analysis. Journal of the American Medical Directors Association. 2022.

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