Nurse practitioner model of care for the initiation of pre-exposure prophylaxis: A case series study.

Only seven men were included, and only four attended the 3-month visit, so the findings cannot show what would happen in a larger group. There was no control group, so changes cannot be attributed to the nurse-led PrEP model rather than time, education, or other care. Adherence relied heavily on self-report, and many participants did not bring medication logs, so missed doses may be undercounted. The clinic was urban and the participants were mostly employed and college-educated, so results may not apply to rural or less resourced settings. Some participants reported inconsistent condom use and said PrEP meant they did not need condoms. The follow-up period was 3 months, so it does not show long-term PrEP retention, adherence, or HIV and STI outcomes.

Do not conclude that the nurse-led PrEP model improves adherence, prevents HIV or STIs, or should replace usual care. Seven men were followed for 3 months without a control group, adherence was mostly self-reported, logs were often missing, and some participants reported inconsistent condom use.