Nurse-Led Pre-Exposure Prophylaxis Delivery to Adolescent Girls and Young Women Accessing Family Planning Services: A Pilot Study in Uganda.
Ivan Segawa, Renee Heffron, Sharon Akello and 3 others
PMID 41557259WHAT IT FOUND
Nurses successfully delivered HIV prevention medication alongside contraception to young women in a busy Ugandan clinic.
Nearly all eligible participants started treatment immediately, and no one acquired HIV during the six-month follow-up period.
Key findings
0159 of 69 eligible young women enrolled, and 92% of eligible participants initiated PrEP on the same day.
02Retention dropped from 83% at one month to 41% at six months, with self-reported good adherence falling from 56% to 29% over the same period.
03The median duration for a nurse-led PrEP enrollment visit was 136 minutes, with routine care tasks taking approximately 95 minutes.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study was a small pilot with only 59 participants, so the results may not reflect how the program performs at scale. Adherence was measured by self-report, which can be influenced by social desirability bias; actual pill-taking may have been lower than reported. Participants were compensated for their visits, which may have improved retention compared to routine care settings without payments. The study took place in a single facility in Uganda, limiting generalizability to other contexts. Nurses were not dedicated solely to PrEP; they balanced these duties with other clinic responsibilities, which may have extended visit times.
Declared interests
The authors report no real or perceived vested interests related to this article that could be construed as a conflict of interest.
The easy way to misread this
Do not interpret the lack of new HIV infections as proof of the program's efficacy. The study was not designed to test effectiveness, had a small sample size, and relied on self-reported adherence which may have been overstated.