Applied Evidence

Non-invasive mechanical ventilation as an adjunct to pulmonary rehabilitation in patients with bronchiectasis: a pathophysiological perspective.

Frontiers in rehabilitation sciences · 2026 · Narrative Review

Jhojan Sebastian Herrera-Vargas, Cristian Jose Gomez-Vega

PMID 42529321

A pathophysiology discussion, not a trial.

No patients, no original results. The authors themselves call the bronchiectasis evidence 'scarce' and say it rests on extrapolation from COPD.

What this paper is

This is a pathophysiological perspective article, not a clinical study. It explains how non-invasive ventilation (NIV) could theoretically reduce the work of breathing in bronchiectasis during pulmonary rehabilitation, and it cites findings from COPD trials to build a biological case. It enrolls no patients, reports no original data, and contains no methods or results of its own. The authors state plainly that no randomized trials in bronchiectasis exist and that the evidence is 'scarce' and based on 'physiological rationale and extrapolations from other obstructive diseases.' There is no finding here to change your practice on.

Declared interests

Funded by Institución Universitaria Visión de las Américas (Research Project P207-2023, Research Projects Call No. 013). No device manufacturer or industry sponsor is named.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →


The study

Certainty of evidence
Low

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    Jhojan Sebastian Herrera-Vargas, Cristian Jose Gomez-Vega Non-invasive mechanical ventilation as an adjunct to pulmonary rehabilitation in patients with bronchiectasis: a pathophysiological perspective. Frontiers in rehabilitation sciences. 2026.

    Read the original — we summarise, we never replace the paper.