PTCohortArchives of physical medicine and rehabilitation2018

Lower Quadriceps Rate of Force Development Is Associated With Worsening Physical Function in Adults With or at Risk for Knee Osteoarthritis: 36-Month Follow-Up Data From the Osteoarthritis Initiative.

Bo Hu, Søren Thorgaard Skou, Barton L Wise and 3 others

PMID 29408538

WHAT IT FOUND

No association was found with worsening on walking or chair-stand tests.

Higher quadriceps rate of force development was linked to less worsening of self-reported function, especially in women.

Key findings

01The highest baseline quadriceps rate of force development tertile had a lower adjusted risk of worsening self-reported physical function over 36 months than the lowest tertile (adjusted OR 0.68, 0.51 to 0.92).

02RFD was not associated with worsening on the 20-meter walk or repeated chair stand over 36 months.

03In sex-specific analyses, women in the highest RFD tertile had a lower adjusted risk of worsening self-reported physical function than women in the lowest tertile (adjusted OR 0.57, 0.38 to 0.86); men did not have a statistically significant reduction in the middle or highest tertiles.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

This was an observational cohort, so it shows association, not that higher RFD caused less functional decline or that training would help. The positive finding was for self-reported WOMAC-PF worsening, not for walking or chair-stand performance. Follow-up was only 36 months, and the authors note functional decline can be slow, which may have made objective changes harder to detect. Analyses used fewer participants than the included cohort because some lacked baseline RFD or follow-up outcome data. RFD was measured only isometrically, and the sample was limited to people with or at risk for knee OA in the Osteoarthritis Initiative cohort.

Declared interests

No author conflict-of-interest declaration is included in the supplied text. The article is listed as supported by NIH extramural and non-U.S. government research support.

The easy way to misread this

Do not conclude that power training will prevent worsening physical function. This study only observed that higher baseline quadriceps rate of force development was associated with less worsening on a self-reported function scale, and it did not find the same association for walking or chair-stand performance.

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The study

Participants
3623 participants were included; analyses were available for 2238 participants for the 20-meter walk, 2017 for the repeated chair stand, and 2630 for the WOMAC-PF.
Certainty of evidence
Low

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Bo Hu, Søren Thorgaard Skou, Barton L Wise, et al. Lower Quadriceps Rate of Force Development Is Associated With Worsening Physical Function in Adults With or at Risk for Knee Osteoarthritis: 36-Month Follow-Up Data From the Osteoarthritis Initiative. Archives of physical medicine and rehabilitation. 2018.

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