CohortAmerican journal of physical medicine & rehabilitation2024

Long-Term Impact of Psychological Rehabilitation on Isolated Hospitalization Patients With COVID-19: A Longitudinal Study.

Jae Hyu Jung, Eun Hui Jeon, Jin Young Ko

PMID 38684140

WHAT IT FOUND

A hospital-based psychological rehabilitation program for COVID-19 patients did not maintain anxiety reduction at six months.

While depression scores remained lower than controls, anxiety worsened significantly after discharge in the treatment group, suggesting short-term inpatient interventions alone may not prevent long-term psychological distress.

Key findings

01The experimental group showed a significant increase in anxiety scores from discharge to the 6-month follow-up, with a steeper deterioration than the control group.

02Depression scores in the experimental group remained significantly lower than the control group at the 6-month follow-up, despite no significant difference in total depression scale scores between groups at that time.

03The effects of the psychological rehabilitation program implemented during the two weeks of hospitalization were not maintained for anxiety until six months after discharge.

STILL TO COME

How it was doneWhat they found

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What it does not show

The study suffered from extremely high attrition, with only 29 of the original 109 patients (approximately 25%) completing the follow-up, which severely limits the generalizability and power of the findings. Missing data was handled by replacing values with the average of respondents within the group, a method that can introduce bias. The follow-up assessment was not planned during the initial trial, which may have contributed to the high non-response rate. The sample size was small, resulting in only small effect sizes being observed. The study population was specific to Korean patients with mild-to-moderate COVID-19 who were hemodynamically stable, so findings may not apply to more severe cases or other cultural contexts.

Declared interests

The paper does not report any conflicts of interest or funding sources in the provided text.

The easy way to misread this

Do not interpret the maintained reduction in depression VAS scores as evidence that the inpatient program was effective long-term. The primary anxiety outcome showed significant deterioration in the treatment group after discharge, and the high dropout rate means these results are likely unreliable for guiding clinical practice.

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The study

Participants
29 patients completed the 6-month follow-up (13 experimental, 16 control) out of 109 originally enrolled
Certainty of evidence
Low

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    Jae Hyu Jung, Eun Hui Jeon, Jin Young Ko Long-Term Impact of Psychological Rehabilitation on Isolated Hospitalization Patients With COVID-19: A Longitudinal Study. American journal of physical medicine & rehabilitation. 2024.

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