RNCohortThe journal of nursing research : JNR2026

Influence of Social Support and Quality of Life on Mortality Among Patients Undergoing Hemodialysis.

Lu Zhang, Yongai Zhang, Sumei Zhang and 4 others

PMID 41805735

WHAT IT FOUND

In adults on maintenance hemodialysis, higher baseline quality of life and higher reported social support were linked to lower 3-year mortality.

Nurses can ask whether patients can actually use available help, not only whether they have family or friends.

Key findings

01During the 3-year follow-up, 73 of the 236 analysed patients died (30.93%).

02After adjustment, each 1-point higher SF-36 score was associated with 1.7% lower mortality risk, and each 1-point higher SSRS score with 3.8% lower mortality risk.

03Patients who died had lower baseline physical and mental component summary scores and lower use of social support than survivors.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The study was observational, so it cannot show that social support or quality of life caused lower mortality. Participants were recruited by convenience sampling from two hospitals, so the results may not apply to other dialysis populations. Only baseline scores were measured, so changes in social support or quality of life over time were not assessed. Patients with cancer, acute infection, severe heart disease, current hospitalization, or inability to cooperate were excluded, so findings may not apply to those groups. Some initially enrolled patients were excluded during follow-up because they transferred, received a transplant, or stopped dialysis; the analysed sample was 236 of the 286 enrolled. Questions about sexual activity were omitted, so that quality-of-life domain was not compared. A results sentence states that hazard ratios below 1 indicated higher mortality risk, while the reported percentage interpretation says each 1-point increase decreased mortality risk.

Declared interests

Funding was from the Natural Science Basic Research Program of Shaanxi Province. The supplied text reports no other conflicts of interest.

The easy way to misread this

Do not conclude that improving social support or quality of life will reduce mortality. This was an observational study, and the authors state it cannot confirm causal relationships.

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