RNMeta-AnalysisHeart & lung : the journal of critical care2022

Incidence of cardiac complications following COVID-19 infection: An umbrella meta-analysis study.

Mehdi Jafari-Oori, Seyed Tayeb Moradian, Abbas Ebadi and 2 others

PMID 35074740

WHAT IT FOUND

In COVID-19 patients, cardiac complications were common: acute myocardial injury 21%, arrhythmia 16%, heart failure 14%.

They were more frequent in severe disease and went with higher ICU admission and death.

Key findings

01Acute myocardial injury was reported in 21% of overall COVID-19 patients.

02In severe disease, acute myocardial injury was 29.67% and shock was 35.2%; in deceased patients, acute myocardial injury was 61% and arrhythmia was 47.56%.

03After duplicate data were removed, the pooled risk ratio for ICU admission was 2.92 and for mortality was 2.57 in patients with acute myocardial injury compared with those without it.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

Most included primary studies were from China, so the findings may not apply everywhere. The work measured new cardiac complications during COVID-19 illness, not pre-existing or overall prevalence of cardiac disease. Several estimates had very high variation between studies, so the pooled percentages are uncertain. Many reviews shared the same primary studies, and removing duplicate data lowered several effect sizes and widened confidence intervals. Publication bias could only be checked for acute myocardial injury, not most other estimates. Some complications, such as pericardial effusion, cardiac insufficiency, cardiomyopathy, and myocardial infarction, were reported in too few reviews to pool reliably. The included reviews were based on observational studies, not tests of treatment or monitoring.

The easy way to misread this

Do not conclude that routine cardiac monitoring will reduce death or ICU admission. The paper reports incidence and associations from observational reviews, not a tested monitoring intervention.

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