PTSLPOtherThe Journal of head trauma rehabilitation2025

Higher Cardiovascular Risk Factor Burden Associated With Cumulative Concussion History and Age-Related Differences.

Benjamin L Brett, Mikaela E Sullivan, Neelum T Aggarwal and 9 others

PMID 41423773

WHAT IT FOUND

In former professional football players aged 50 or younger, a higher number of prior concussions was associated with greater odds of hypertension and high cholesterol.

This association was not found in players older than 50.

Key findings

01Greater history of prior concussion was more strongly associated with higher odds of hypertension and hyperlipidemia in the younger former athlete group compared to the older athlete group.

02In players aged 50 or younger, those with 10 or more prior concussions had significantly higher odds of hypertension compared to those with no prior head injuries.

03The presence of cardiovascular risk factors was disproportionately associated with worse functioning across multiple domains in younger, as compared to older, former athletes.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for SLPs

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What it does not show

The study is cross-sectional, so it cannot determine whether concussions caused the cardiovascular issues or if other factors were involved. All data, including concussion counts and medical diagnoses, were self-reported, which may introduce recall bias. The sample consisted exclusively of former professional football players, so findings may not apply to other athletes or the general population. Survival bias may affect the older group, as those with severe health issues may have died before being recruited.

The easy way to misread this

Do not assume that concussions directly cause hypertension or high cholesterol. This study shows an association in a specific group of former athletes, but because it is cross-sectional, it cannot prove causation. Other lifestyle or biological factors may explain the link.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →