ProtocolDisability and rehabilitation. Assistive technology2024

Feasibility, acceptability, and initial efficacy of a wheelchair exercise training program in persons with multiple sclerosis: study protocol for a parallel group randomized controlled trial.

Stephanie L Silveira, Robert W Motl, Katherine Froehlich-Grobe and 1 others

PMID 38520055

WHAT IT FOUND

This is a protocol for a planned trial, not a report of results.

It describes testing a 16-week remote exercise program for wheelchair users with MS. No patients have been treated yet, so there are no findings on whether the program works.

Key findings

01The study is a protocol for a future randomized controlled trial assessing feasibility and preliminary efficacy, not a completed trial with results.

02The intervention involves a 16-week home-based exercise program with behavioral coaching, compared to a wellness control group that avoids exercise topics.

STILL TO COME

How it was done

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What it does not show

No patients have been enrolled or treated, so no data on effectiveness, safety, or feasibility exists. The planned sample size of 24 is too small to detect meaningful clinical differences or generalize to the broader MS population. The study is designed to test if the trial *can* be done, not if the treatment *works*.

Declared interests

The authors report no competing interests to declare.

The easy way to misread this

Do not interpret this as evidence that the exercise program works. It is a plan for a future study; no participants have received the intervention and no outcomes have been measured.

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The study

Participants
24 planned
Certainty of evidence
Very low

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    Cite

    Stephanie L Silveira, Robert W Motl, Katherine Froehlich-Grobe, et al. Feasibility, acceptability, and initial efficacy of a wheelchair exercise training program in persons with multiple sclerosis: study protocol for a parallel group randomized controlled trial. Disability and rehabilitation. Assistive technology. 2024.

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