Factors Influencing HPV Vaccination Uptake in Adolescents: Evidence to Guide Clinical Practice.
Taylor Mullin, Diane Von Ah
PMID 41709414WHAT IT FOUND
Clear provider recommendation was linked to starting and finishing HPV vaccines in every study that measured it.
Parental knowledge and attitudes were less consistent, so clinicians should not assume parental hesitancy is the main barrier.
Key findings
01All 21 studies examining provider recommendation found a positive association with HPV vaccine initiation, and all 23 studies assessing it found a positive association with completion.
02Rural residence was associated with lower initiation in 19 of 24 studies and lower completion in 15 of 20 studies.
03Parental knowledge and attitudes were less consistent than structural and provider-related factors.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The included studies were mostly retrospective or cross-sectional, so associations cannot prove cause. Findings were narratively synthesized, not pooled into a single estimate. Many studies were region-specific, so results may not apply everywhere. Definitions of initiation, completion, uptake, and adherence varied across studies. Self-reported data may introduce recall bias. Parental knowledge and attitude findings were inconsistent. Only U.S. studies were included.
Declared interests
The authors declared no conflicts of interest.
The easy way to misread this
Do not treat provider recommendation as a proven way to increase vaccination. The review found consistent associations in observational studies, not randomized trials that prove cause.