Factors associated with the evolution of COVID-19 in pregnant women: a Brazilian population-based study.
Luis Henrique de Andrade, Gustavo Gonçalves Dos Santos, Mônica Aparecida de Paula de Sordi and 2 others
PMID 38051223WHAT IT FOUND
In 6,276 pregnant women with confirmed COVID-19, dyspnea and oxygen saturation ≤95% were associated with about two times higher ICU risk; invasive ventilation was associated with about 10 times higher death risk.
Later trimesters, comorbidities, and age over 34 were associated with worse outcomes.
Key findings
01In the final model, dyspnea and oxygen saturation equal to or less than 95% were independently associated with ICU admission, with the largest effects about two times higher risk.
02Needing invasive ventilation was associated with about 10 times higher death risk in the final model.
03ICU admission occurred in 28.2% and death in 9.5% of 6,276 pregnant women.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study used a government surveillance database, so the findings depended on the quality and completeness of notifications by health professionals. Some cases may not have had time to be fully updated, which could underestimate ICU admission or death. Blank entries for comorbidities, signs, and symptoms were counted as absent, which may misclassify women. Women without final evolution or without all information of interest were excluded, leaving 6,276 analysed. Because this was an observational cross-sectional analysis, it reports associations and cannot show that any factor caused ICU admission or death.
The easy way to misread this
Do not read the invasive ventilation association as proof that ventilation caused death. The study reports associations from a surveillance database and cannot show that any factor caused ICU admission or death.