Factors associated with sleep quality during chemotherapy: An integrative review.
Regina Claudia da Silva Souza, Maiara Rodrigues Dos Santos, Izabel Alves das Chagas Valota and 2 others
PMID 32802348WHAT IT FOUND
Pain, fatigue, depression, distress, and anxiety were the most consistently associated factors with poor sleep quality in cancer patients undergoing chemotherapy.
Older age, lower physical functioning, and more comorbidities were also linked to sleep disturbances.
Key findings
01Pain, fatigue, depression, and distress were the most prevalent symptoms associated with sleep disturbances in patients undergoing chemotherapy.
02Advanced age, poor physical functioning, and a high number of comorbidities were identified as predisposing factors for sleep disturbances.
03Distress and anxiety symptoms were significantly associated with the presence of sleep disturbances.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for RNs
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What it does not show
All included studies were observational (cohort or cross-sectional), which limits the ability to establish causality. Only two of the sixteen studies used a control group. The review found a wide variety of sleep assessment instruments, making direct comparison of results difficult. The therapeutic regimen (specific chemotherapy drugs) was not described in the included studies, which could influence sleep outcomes.
The easy way to misread this
Do not assume these factors cause sleep disturbances. The review included only observational studies, which identify associations but cannot prove that treating pain or fatigue will directly improve sleep quality.