RNOtherJournal of the American Medical Directors Association2026

Exposure to Drugs Related to Injurious Falls Risk and to Bisphosphonates in Nursing Home Residents With Recent Fracture.

Jimmie E Roberts, Andrew R Zullo, Derrick Lo and 2 others

PMID 42632250

WHAT IT FOUND

Nursing home residents with recent fracture rarely used oral bisphosphonates, only 4.2%, while 72.8% used at least one medication linked to injurious falls.

Residents on bisphosphonates did not have fewer high-risk medications.

Key findings

01Only 4.2% of nursing home residents with a recent fracture used oral bisphosphonates.

0272.8% used one or more drug classes linked to injurious falls risk, and the mean number of classes was 1.9.

03Residents using bisphosphonates had a higher mean number of falls-risk drug classes than non-users, 2.1 versus 1.9.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

Read the rest of this summary

You get three full summaries a month, free, and we do not ask for a card. Search, the TL;DRs and your library stay unlimited either way.

Already have one?

What it does not show

It describes medication use only in the 30 days before a fixed index date, so it cannot show what happened after the fracture or whether medication changes caused falls or fractures. Residents enrolled in Medicare Advantage were excluded, and their medication use may differ from fee-for-service residents. Some residents prescribed oral bisphosphonates before the 30-day lookback period may have been counted as non-users, although the authors expected this misclassification to be limited. The study counted medication classes and days supplied, not doses or number of medications within a class, so it cannot show how much drug each resident received. Non-hip fractures were not categorized further, so findings may differ across fracture types. It assessed only oral bisphosphonates, not other osteoporosis treatments, so total osteoporosis treatment may be underestimated.

The easy way to misread this

Do not read the low oral bisphosphonate use and high falls-risk medication use as proof that changing medications will reduce future falls or fractures. The study described medication use in a 30-day window and did not test treatment changes or follow outcomes.

Read it on PubMed →

Exposure to Drugs Related to Injurious Falls Risk and to Bisphosphonates in Nursing Home Residents With Recent Fracture. — Applied Evidence