RNOtherJournal of infusion nursing : the official publication of the Infusion Nurses Society2017

Evaluation of Compatibility of a Gum Mastic Liquid Adhesive and Liquid Adhesive Remover With an Alcoholic Chlorhexidine Gluconate Skin Preparation.

Marcia Ryder, Collette Duley

PMID 28683004

WHAT IT FOUND

A gum mastic liquid adhesive or adhesive remover applied over chlorhexidine-alcohol skin prep did not weaken bacterial control at 3 or 7 days versus prep alone in healthy volunteers.

Key findings

01Adding a gum mastic liquid adhesive or a liquid adhesive remover to alcoholic chlorhexidine did not significantly change mean log10 reductions from baseline at 3 or 7 days compared with alcoholic chlorhexidine alone.

02There was no statistically significant effect of product or day on microbial reductions, and no product-by-day interaction.

03No adverse events or skin reactions were observed during the study.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

Small sample size. Healthy volunteers with intact skin, not patients with catheters or altered skin flora. Lack of racial diversity. The outcome was skin bacterial counts, not catheter-related bloodstream infection, dressing failure, or patient harm. Only two named commercial products were tested, so other adhesives or removers may behave differently.

The easy way to misread this

Do not conclude that these adhesives prevent infection. The study measured bacterial counts on healthy volunteer skin and found no significant difference from chlorhexidine-alcohol alone, not a reduction in catheter-related bloodstream infection.

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