PTOtherJournal of neuroengineering and rehabilitation2025

Enhanced gastrocnemius-mimicking lower limb powered exoskeleton robot.

Tianchi Chen, Zhi Liu, Chaoyang Li and 3 others

PMID 40760664

WHAT IT FOUND

In five healthy men, a gastrocnemius-mimicking exoskeleton reduced calf muscle activation during walking and squat holding and increased squat-holding endurance 7.79 times, but it was tested only in healthy volunteers.

Key findings

01Active assistance reduced mean gastrocnemius activation during level walking compared with no device at 1 km/h, 2 km/h, and 3 km/h.

02Active assistance reduced mean gastrocnemius activation by 59.8% over the short-duration squat holding experiment compared with no device.

03Participants wearing the assisted exoskeleton sustained long-duration squat holding for 7.79 times longer on average than without it.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The human tests included only five healthy adult men, so they do not show what would happen in patients. The paper states the findings may not be directly applicable to people with muscle injuries or neurological conditions. The tasks were short treadmill walking and squat holding, not a rehabilitation programme or daily activities. The authors did not address how the exoskeleton affects coordination between the knee and ankle. The simulation used a simplified lower limb model, so it is not evidence of human clinical benefit. The paper does not report randomisation, blinding, dropouts, or patient outcomes.

Declared interests

The paper names the Graduate Scientific Research and Innovation Foundation as funder. It does not report a conflict-of-interest declaration.

The easy way to misread this

Do not read the 7.79 times longer squat endurance as proof that this exoskeleton helps patients. It was measured in five healthy men, and the paper says the findings may not apply to people with muscle injuries or neurological conditions.

Read it on PubMed →