RNRCTThe journal of nursing research : JNR2026

Effects of Motivational Interview-Based Cognitive Therapy in Patients With Schizophrenia: A Multicenter Randomized Controlled Trial.

Yan-Liang Chen, Chieh-Yu Liu, Chiu-Yueh Yang

PMID 42579517

WHAT IT FOUND

In patients with schizophrenia spectrum disorders who took medication irregularly, eight nurse-delivered sessions of motivational interview-based cognitive therapy improved adherence more than routine care at 24-32 weeks, not at four sessions.

Insight and positive symptoms also improved more than routine care.

Key findings

01At postintervention, MIBCT improved medication adherence more than routine care (B=2.56, p<.001, effect size 0.912), but there was no significant between-group difference at the fourth session.

02Insight into illness improved more with MIBCT than routine care by 1.85 points at the fourth session and 2.23 points at postintervention.

03Positive symptoms improved more with MIBCT than routine care by 2.52 points at the fourth session and 1.85 points at postintervention.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

Read the rest of this summary

You get three full summaries a month, free, and we do not ask for a card. Search, the TL;DRs and your library stay unlimited either way.

Already have one?

What it does not show

Only Chinese-reading patients aged 20 to 64 with schizophrenia spectrum disorders who were stable enough to consent were included, so results may not apply to people with cognitive impairment, substance use, severe communication problems or other severe mental illness. The study was done in two psychiatric teaching hospitals in northern Taiwan, so it may not generalise to other settings. Attrition was substantial: 21% at the fourth session and 9% at postintervention, and the limitations section reports 30% attrition. Follow-up stopped at 32 weeks, so long-term adherence after the intervention is unknown. Medication adherence was self-reported, and the authors note that nursing staff reminders may have inflated baseline scores. All participants continued usual psychiatric care, and MIBCT combined motivational interviewing, cognitive strategies and psychoeducation, so the contribution of each component cannot be separated. Only a master's-level psychiatric nurse with specific motivational interviewing training delivered the intervention, so routine delivery by ordinary nursing teams is not shown.

The easy way to misread this

Do not conclude that MIBCT alone is responsible for the improvement or that it works long term. All participants continued usual psychiatric care, MIBCT combined motivational interviewing, cognitive strategies and psychoeducation, follow-up stopped at 32 weeks, and the primary adherence outcome was not significantly different at the fourth session.

Read it on PubMed →