PTRNMeta-AnalysisNursing open2021

Effects of high-intensity interval training in patients with coronary artery disease after percutaneous coronary intervention: A systematic review and meta-analysis.

Xinyue Zhang, Dongmei Xu, Guozhen Sun and 3 others

PMID 33528117

WHAT IT FOUND

Supervised high-intensity interval training after PCI did not change heart rate, LDL, or triglycerides, but it raised peak oxygen uptake and reduced late luminal loss in 6 small trials.

Key findings

01HIIT increased peak oxygen uptake in 3 trials involving 133 patients.

02HIIT reduced late luminal loss in 2 trials involving 76 patients.

03HIIT did not significantly change heart rate, LDL, or triglycerides.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for RNs

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What it does not show

Only 6 trials and 247 patients were included, and the number was too small for a funnel plot. The control groups were mixed, including usual care and moderate-intensity exercise. Randomization and allocation concealment were reported in 2 trials, and blinding was mostly unclear. Important intervention details were missing or incomplete, including modes of delivery, tailoring, and modifications. The trials used different HIIT protocols, start times, session frequencies, and durations. The supplied text does not name a single primary outcome.

Declared interests

The supplied text states that the work was supported by the National Natural Science Foundation of China. It does not provide author conflict-of-interest declarations.

The easy way to misread this

Do not conclude that HIIT is proven for every patient after PCI. The positive findings came from 6 small trials with unclear blinding and mixed control groups, and heart rate, LDL, and triglycerides did not change.

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