RNMeta-AnalysisNursing open2025

Effectiveness of Nursing Care Intervention for Patients With Pulmonary Tuberculosis: A Systematic Review and Meta-Analysis.

Yumei Yan, Xue Bai

PMID 40460186

WHAT IT FOUND

Nursing care packages for pulmonary TB were linked to higher medication compliance, better psychological and social function, lower anxiety and depression, and fewer adverse reactions.

Knowledge gains were not confirmed.

Key findings

01In 8 studies with 1059 participants, the pooled odds ratio for medication compliance was 3.601 (95% CI 2.366 to 5.481), favouring nursing care over standard care.

02In 5 studies with 666 participants, anxiety scores were lower with nursing care (pooled SMD -2.728, 95% CI -4.354 to -1.102); in 3 studies with 318 participants, depression scores were lower (pooled SMD -1.389, 95% CI -2.706 to -0.072).

03Disease knowledge gains were not confirmed: the pooled odds ratio was 4.791 (95% CI 0.770 to 29.807) across 3 studies with 239 participants.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

Only one researcher screened titles, abstracts and full texts. Six of 16 studies were rated high risk of bias and six had some concerns, with only four low risk. The included studies used different nursing care packages and different comparators, and the review could not isolate which component mattered. For psychological function, social function, anxiety and depression, the pooled results varied greatly between studies. Publication bias could not be assessed because too few studies were included. The evidence came mainly from China, with studies also from Indonesia, Spain and Nigeria. The disease knowledge outcome was not confirmed. The review included quasi-experimental and observational studies as well as randomised trials.

Declared interests

The authors declared no conflicts of interest.

The easy way to misread this

Do not conclude that any specific nursing activity improves pulmonary TB outcomes. The review combined different nursing care packages, many studies had high risk of bias, and the knowledge outcome was not confirmed.

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