Effectiveness of Buffered Lidocaine for Local Anesthesia During Liver Biopsy.
Deborah Hockett, Laura Kress, Ryan Mac Donald and 2 others
PMID 33927155WHAT IT FOUND
Patients who received buffered lidocaine for liver biopsy reported less pain after injection than patients who received lidocaine plus sterile water.
Anxiety did not differ between groups.
Key findings
01Mean postprocedure pain was 1.65 in the buffered lidocaine group and 2.27 in the control group.
02Mean pain change was 0.93 in the buffered lidocaine group and 1.63 in the control group.
03Anxiety scores ranged from 2.55 to 2.87 and did not differ between the buffered lidocaine group and the control group.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
It was done at one inner-city community hospital, so results may not apply to other settings. Fasting instructions were more common in the intervention group, although the analysis adjusted for this. Buffered lidocaine is not commercially available and must be prepared shortly before use. The prepared solution was stable for 24 hours only if refrigerated. One study ID was double counted and removed. The trial did not test whether the effect applies to other procedures.
Declared interests
The authors declared no conflicts of interest.
The easy way to misread this
Do not conclude that buffered lidocaine reduces anxiety. Anxiety scores did not differ between groups, even though postprocedure pain was lower.