RNSystematic ReviewGastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates2025

Effect of Cognitive Behavior Therapy on the Mental Health of Patients With Irritable Bowel Syndrome: A Systematic Review.

Yingyu Liu, Xuping Pan

PMID 41128451

WHAT IT FOUND

In adults with IBS, CBT was linked to improvements in anxiety, depression, sleep, quality of life, or symptom-related disability in many included studies, but not all.

A mobile CBT study did not reduce IBS symptoms or quality of life.

Key findings

01CBT-based interventions for IBS patients with psychological distress improved emotion regulation, anxiety, depression, and lifestyle measures.

02A CBT-based mobile application enhanced cognition and behavior but had no significant effect on IBS symptoms or quality of life.

03Therapist-delivered and web-based CBT substantially improved IBS symptoms and social and occupational adjustments.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The review did not analyze subgroups by IBS severity, comorbid mental health conditions, or CBT characteristics. The review did not directly compare CBT delivery formats, such as face-to-face, online, and mobile apps. The included studies were heterogeneous in design, sample size, intervention content, duration, and outcomes, with participants ranging from 8 to 558 and interventions lasting from 4 weeks to 24 months. The stated inclusion criteria allowed cross-sectional studies, while the exclusion criteria removed them; the final set also included observational and prospective studies. Some studies did not report long-term follow-up.

The easy way to misread this

Do not conclude that CBT reliably improves IBS symptoms or quality of life for every patient. Several studies reported improvements in anxiety, depression, sleep, or symptom-related disability, but a mobile CBT study had no significant effect on IBS symptoms or quality of life, and the review did not compare delivery formats.

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