RNNarrative ReviewJapan journal of nursing science : JJNS2025

Depressive symptoms and heart rate variability in perinatal women: A narrative review.

Taeko Unno, Hisayo Okayama

PMID 39871758

WHAT IT FOUND

In perinatal women, heart rate variability was associated with stress, anxiety, and depressive symptoms in some studies, but results were inconsistent.

Slow-breathing HRV biofeedback showed some reported benefit. Treat it as an adjunct, not a replacement for clinical assessment.

Key findings

01Across studies that measured heart rate variability at the same time as symptoms, links were inconsistent: anxiety was associated in one of four studies, depression in four of seven, and stress in three of four.

02Three studies found that heart rate variability during pregnancy predicted postpartum depression, while one study found no such association.

03Two included heart rate variability biofeedback studies reported reduced depression or stress compared with no therapy, and one no-control study reported improved anxiety.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

This is a narrative review, not a controlled trial, and it does not show that heart rate variability can diagnose or prevent postpartum depression. The included studies used different heart rate variability measures, devices, settings, and symptom scales, making direct comparison difficult. Many studies had small samples, and the authors said the load-test studies were too few to identify trends. Some studies did not control for factors that can affect heart rate variability, such as breastfeeding, motion, posture, time of day, and pregnancy stage. Intervention studies were mixed: some did not use a control group, some did not measure heart rate variability, and one mindfulness study found heart rate variability moved opposite to the expected direction.

Declared interests

The authors declared no conflict of interest.

The easy way to misread this

Do not conclude that wearable heart rate variability monitoring or heart rate variability biofeedback is proven to prevent or treat perinatal depression. The associations were inconsistent, the intervention evidence was small and mixed, and standard symptom assessment remains necessary.

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