COVID outbreak after the 1st dose of COVID vaccine among the nursing home residents: What happened?
Ping Ye, Liam Fry, Haiyan Liu and 2 others
PMID 34274688WHAT IT FOUND
In this nursing home outbreak, the first dose did not lower infection rates, but both doses were associated with lower infection risk.
Among residents diagnosed during the partially vaccinated period, 24 of 30 were asymptomatic.
Key findings
01Residents who received both vaccine doses had a lower relative risk of infection than residents who received only the first dose (relative risk 0.37, p < 0.01).
02No residents more than 7 days after the second dose were diagnosed with COVID-19 during the study period.
03The partially vaccinated group did not have lower infection incidence, and the relative risk of symptomatic cases was 0.68 (p = .220).
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study was in one nursing home with 91 residents, so results may not apply elsewhere. Only 17 residents received the second dose, so the comparison for full vaccination was small. Case dates depended on testing schedules, and some infections may have begun earlier than they were diagnosed. The observation period was only two months. The sample was too small to statistically compare hospitalization and death rates.
The easy way to misread this
Do not conclude that partial vaccination alone reliably prevented infection or severe outcomes. The partially vaccinated group did not have lower infection incidence, and the relative risk of symptomatic cases was 0.68 (p = .220).