COVID-19 and New Onset IgA Vasculitis: A Systematic Review of Case Reports.
Assylzhan Messova, Lyudmila Pivina, Zhanna Muzdubayeva and 3 others
PMID 35691763WHAT IT FOUND
In 13 cases of new IgA vasculitis with SARS-CoV-2, 8 were adults and 7 had renal involvement.
Emergency nurses should watch for palpable purpura, abdominal pain, joint swelling, and urine abnormalities, even when respiratory symptoms are absent.
Key findings
01Among 13 included cases, 8 were adults and renal involvement was found in 7 cases.
02Four patients had no respiratory symptoms and only 3 had pneumonia, so obvious respiratory illness was not always present.
03The review states that almost all cases had a positive effect attributed to glucocorticoids, but the included cases often received several treatments at the same time, so the contribution of any single component cannot be separated.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The review included only 13 case reports, so it cannot show how common this is or prove SARS-CoV-2 caused IgAV. The included reports did not always give exact dates or methods for diagnosing COVID-19 and IgAV. Published case reports may reflect clinician and publication bias. The claim that IgAV affects men is premature. No controlled comparison was available, and patients often received multiple treatments at once, so treatment effects cannot be isolated.
Declared interests
The authors reported no conflicts of interest.
The easy way to misread this
Do not conclude that SARS-CoV-2 caused IgAV or that glucocorticoids alone improved outcomes. This is a review of case reports with no comparison group, and the included patients often received several treatments at the same time.