PTRCTHong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao2026

Comparison of the short-term effects of Mulligan and Maitland mobilisation techniques combined with home-based exercise for non-specific neck pain: A randomised controlled trial.

Ioannis Kiouloukiotis, Evangelos Stathis, Paris Iakovidis and 5 others

PMID 42016050

WHAT IT FOUND

Mulligan and Maitland mobilisation, each added to a daily home exercise programme, were no better than the exercises alone for pain, neck movement, pressure pain threshold or fear of movement after two weeks.

All three groups improved.

Key findings

01Pain fell in all three groups, but no group did better than another: the comparison between groups found no significant difference.

02No mobilisation technique proved superior for neck movement, pressure pain threshold or fear of movement.

03Disability scores fell furthest in the two manual therapy groups and the pattern of change differed between groups, but no pair of groups differed significantly when compared directly.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

Only two weeks and four sessions, with no follow-up, so the study says nothing about whether a difference would appear or last with a longer course of treatment. Participants and treating therapists knew which treatment was being given, and the exercise-only group had no supervised sessions at all. The extra therapist contact in the two mobilisation groups could explain why those groups did better on disability, fear of movement and catastrophising. Participants were 18 to 40, mostly physically active and had low baseline disability, so the results may not transfer to older or less active patients, or to those with more severe disability or other conditions. The sample was small, 43 people, from a single university department over a two-month period. Non-specific neck pain covers a mixed group of presentations, and mobilisation was applied to the most painful spinal level rather than matched to each person's movement problem.

Declared interests

The authors state that the research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors, and they declared no conflict of interest.

The easy way to misread this

Do not read the disability result or the catastrophising comparison as evidence that mobilisation beats exercise alone. The pattern of change for disability differed between groups overall, but no two groups differed significantly when compared head to head, and the catastrophising result was a single comparison against the exercise-only group while the overall test between groups was not significant.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →


The study

Participants
43 (no dropouts)
Certainty of evidence
Moderate

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Cite

Ioannis Kiouloukiotis, Evangelos Stathis, Paris Iakovidis, et al. Comparison of the short-term effects of Mulligan and Maitland mobilisation techniques combined with home-based exercise for non-specific neck pain: A randomised controlled trial. Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao. 2026.

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