PTOTOtherJournal of occupational rehabilitation2026

Changes in Pregabalin Dispensing to Australians with Workers' Compensation Claims for Low Back Pain Following the Listing of Pregabalin on the Pharmaceutical Benefits Scheme.

Michael F Di Donato, Christina Abdel Shaheed, Alex Collie and 2 others

PMID 39939569

WHAT IT FOUND

Listing pregabalin on Australia's subsidised drug scheme caused dispensing to workers' compensation patients with low back pain to increase sharply.

The proportion of workers receiving it rose from 6.6% to 17.0%, and time to first dose dropped from 284 days to 84 days.

Key findings

01The percentage of workers with low back pain claims dispensed pregabalin increased from 6.6% before subsidy listing to 17.0% after listing.

02The median time to first pregabalin dispensing decreased from 284 days before listing to 84 days after listing.

03Pregabalin dispensings increased by 26.3% and the cost per dispensing decreased by 61.8% following the PBS listing.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

The data only captured medicines funded by workers' compensation, missing those paid for by private insurance or out-of-pocket. The sample was restricted to workers with claims involving at least two weeks off work, potentially excluding milder cases. Few workers were dispensed pregabalin in the pre-listing group, which may reduce the precision of estimates for that period. The study could not determine if the increase was due to the subsidy itself or broader trends in prescribing and marketing.

Declared interests

The study was funded by the National Health and Medical Research Council and Monash University. No specific commercial conflicts of interest with drug manufacturers were declared in the provided text, though the discussion notes manufacturer-led education campaigns occurred during the study period.

The easy way to misread this

Do not interpret the increase in pregabalin dispensing as evidence that the drug is effective for low back pain. The study reports changes in availability and cost, not clinical outcomes, and the introduction notes that gabapentinoids are not effective for this condition.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →